So I just set up a few new laptops with Vista. They connect via OWA to our 2003 exchange server. I started getting a few people telling me that when they connect to email and try to send or reply the window opens, but there is an X in the box and they can’t type.
I had them click on the options button at the lower left and go to Email Security and Click Install
This seemed to fixed this, but everytime they went to send an email IE7 would crash! yey!!
Turns out I had to download and exchange 2003 patch. You can find it here http://support.microsoft.com/default.aspx/kb/911829/
After I did this all was good with the world. lol. On the laptop that I downloaded the S/MIME i had to go to options and email security and hit reinstall. On the other laptop I never made any changes and it just worked after the exchange server update.
Hope this helps someone out there.